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A team of scientists who analyzed the brain tissue of renowned NFL linebacker Junior Seau after his suicide last year have concluded the football player suffered a debilitating brain disease likely caused by two decades worth of hits to the head, researchers and his family exclusively told ABC News and ESPN.

In May, Seau, 43 — football’s monster in the middle, a perennial all-star and defensive icon in the 1990s whose passionate hits made him a dominant figure in the NFL — shot himself in the chest at his home in Oceanside, Calif., leaving behind four children and many unanswered questions.

Seau’s family donated his brain to neuroscientists at the National Institutes for Health who are conducting ongoing research on traumatic brain injury and football players.